SfN Neuroblogging: BMI and the Brain, SERT and rats, and reading

Nov 15 2011 Published by under SFN Neuroblogging

The SfN Neuroblogging posts are coming thick and fast! Make sure you head over to Scientific American and check out the latest posts from the Society for Neuroscience conference, including posts on grey matter and BMI, the serotonin transporter and animal models of depression, and how we process silently read text. Register to leave comments there, or start a conversation here! Keep the neuroscience flowing!

2 responses so far

  • Seamonkey says:

    Here b/c I don't want to register @ SA (sorry!)

    Anyway, the BMI thing is interesting. I'm quite a few years out of volumetric MRI so I won't comment on that. But there is a definite connection between adipocyte production of immune factors such as IL-6 and CRP and BMI. IL-6 is produced by adipocytes, so even a person at a healthy weight but an unhealthy tissue distribution could be cranking out inflammatory proteins, which in some cases can traverse the BBB.

    Some people envision excess adiposity as an inflammatory condition. So perhaps there may be chronic inflammation leading to neurodegeneration? Not sure how to think about the regional stuff. Perhaps subthreshold decreases in satiety? Depression? (There's a connection between inflammation and depression too.)

    Gotta make it to SfN next year.

    • scicurious says:

      Great minds think alike, and a lot of great minds are on the inflammatory cytokine pathway. I noticed that it and sex differences are two of the really hot things going on this year. For grey matter, I'm not sure, but I know in depression and stress right now it's hot stuff.